Peripheral neuritis is a general term for multiple peripheral nerve damage caused by multiple causes, manifesting as symmetrical sensory, motor and vegetative nerve dysfunction in the distal extremities. It is most commonly seen with B vitamin deficiency, diabetes, uremia, chronic gastrointestinal diseases, pregnancy, etc.; drugs such as furacilin, isoniazid, streptomycin, phenytoin sodium, carbamazepine, vincristine, and organic compounds such as organophosphorus pesticides. Other: such as connective tissue diseases, various cancers of the body can also cause polyneuritis. The main manifestation is numbness in the hands and feet or extremities, which may be accompanied by pain and weakness. In mild cases, numbness at the ends of the fingers (toes) may extend to the entire hand and foot, limbs, or even the whole body in severe cases. Feel numbness and distension, flexion and extension, inflexible movement, “ants crawling like” or “pins and needles-like feeling”, some patients have “socks” “cuffs Some patients have “sock” or “cuff” type abnormal sensation, and they feel that their skin is thickening and their senses are dull. Many patients often have episodes during sleep at night, to numb awake, or wake up in the morning after the hands sleepy, numbness and discomfort stiff feeling, can be relieved after a little activity. The above symptoms are often aggravated after cold and exertion. It is accompanied by fatigue, cold hands and feet, etc. Treatment is based on symptomatic medication, commonly used drugs are as follows: 1, vitamin B1, B6, vitamin B12, vitamin C, rutin tablets, methylcobalamin, Anvi capsule; 2, intravenous infusion: cytarabine, 654-2, salvia injection, etc.; 3, hormone therapy; 4, dibazol, coenzyme Q10 ATP, coenzyme A, cytochrome C.