If the infarction is in the frontal lobe of the brain, personality changes can occur. The big change of personality after cerebral infarction may be the patient’s anxiety and depression after stroke, for this situation, medication to improve anxiety and depression can be given, commonly used are Escitalopram Oxalate, Dextran, all can be improved. If a patient has a big change in personality after a cerebral infarction, family members, especially those close to the patient, must be patient and instruct the patient not to lose their temper. If the personality changes very seriously and there is no way to control it, only appropriate sedative drugs, such as diazepam, can be given to calm the patient down.