Eosinophilic granulomatous vasculitis is a rare immunologic disease that requires appropriate etiologic treatment and symptomatic supportive therapy. 1. Etiologic treatment: after the onset of eosinophilic granulomatous vasculitis, it often leads to allergic inflammation of pulmonary blood vessels, systemic joints and skin, etc. The patient has fever, fatigue, weight loss and other abnormal symptoms, and can be treated with glucocorticosteroids, such as prednisone, immunosuppressant agents such as cyclophosphamide, and biologics, such as rituximab, etc., in accordance with the doctor’s instructions. 2. Symptomatic supportive treatment: patients need to pay attention to strengthening nutrition, if fever, but also active physical cooling, which can reduce the patient’s pain, help the recovery of the disease. Eosinophilic granulomatous vasculitis may cause extensive tissue damage, it is recommended that patients go to the hospital in a timely manner, under the guidance of a professional doctor for treatment, and usually also pay attention to a light diet and proper rest.