It is possible that urolithiasis may require trips to the restroom every half hour, or at intervals of ten minutes. The most common and typical symptoms of uremia are exceptional thirst and heavy urination, often accompanied by hypotonic polyuria. Depending on the degree of the disease, the urine output of patients with uremic avalanches can be as high as 4~10L in a day, but usually does not exceed 18L. Patients with partial uremic avalanches have milder symptoms, and the 24-hour urine output is usually 2.5~5L. Patients may need to go to the toilet every half an hour, or at intervals of more than ten minutes. The color of the patient’s urine is almost the same as that of water, the specific gravity of urine is often below 1.005, due to hypertonicity causes polyuria, the patient’s hypothalamic thirst center hyperactivity, the patient is commonly accompanied by irritability, extreme thirst and drink a lot of water, and like to eat cold drinks. If the patient is not feeling well, he should consult the doctor for examination and early treatment.