Clopidogrel can be combined with ginkgo biloba extract. Clopidogrel belongs to the antiplatelet drugs, clinically used in the treatment of ischemic cardiovascular and cerebrovascular diseases, such as angina pectoris and myocardial infarction caused by coronary heart disease, and cerebrovascular diseases such as cerebral infarction, etc. It can inhibit the aggregation of platelets, improve the arterial blood supply, and prevent the formation of thrombus. Ginkgo biloba extract, the main component of which is ginkgolide, also has the effect of improving local blood supply, and can be used in the treatment of heart disease, cerebrovascular disease, peripheral vascular lesions, the two drugs can play a synergistic effect when used together, and there is no contraindication to the combined use of the two drugs. Clopidogrel’s adverse reactions are mainly based on bleeding, most patients can be manifested as bleeding of the skin mucous membranes, a few patients can occur gastrointestinal bleeding, very few patients will occur cerebral hemorrhage, allergic to the drug components, active bleeding patients are prohibited. Adverse reactions of Ginkgo biloba extract include fever, dyspnea, facial flushing, decreased blood pressure, headache, dizziness, etc. It is contraindicated in patients who are allergic to the drug components, neonates and infants. Clopidogrel and ginkgo biloba extract combined at the same time is beneficial to the treatment of the disease, but the specific use of medication should follow the doctor’s instructions.