You can’t judge whether the patient’s condition is serious only from the high immunoglobulin G. Instead, you have to make a comprehensive analysis from the causes of the high immunoglobulin G, the specific situation and other aspects. Immunoglobulin G is lgG, immunoglobulin G has the function of anti-virus, neutralization of virus, antibacterial and immune regulation, it is the main component of immunoglobulin in the blood of human body, and part of autoantibodies are also belong to immunoglobulin G. Therefore, the elevation of immunoglobulin G may be related to infections, hematological system diseases and autoimmune disease. In addition to bacterial, viral and allergic reactions, elevated lgG monoclonal can also be seen in myeloma, macroglobulinemia, cryoglobulinemia, malignant lymphoma and other hematologic diseases, as well as autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis, and chronic active hepatitis, tuberculosis, and heavy chain disease. High immunoglobulin G should be further improved according to the specific situation, such as autoantibodies, blood sedimentation, CRP, ultrasound, CT and other auxiliary tests to clarify the causes of immunoglobulin G and analyze the severity of the patient’s condition according to the specific causes and manifestations of the disease. Test results need to be interpreted by a professional physician, and it is recommended that patients go to the rheumatology and immunology departments of regular hospitals for detailed consultation, rather than making their own judgments.