Gallbladder adenomyosis is a common gallbladder disorder in hepatobiliary surgery, which is characterized by the proliferation of the mucosa of the gallbladder into the muscularis propria, resulting in thickening of the muscularis propria at the same time. The clinical symptoms are similar to those of gallbladder stones and chronic cholecystitis, and elective surgery is recommended. Adenomyosis of the gallbladder is a not uncommon gallbladder disease, the cause of which is not clear. It is mostly seen in people aged 50-59 years old, and is often accompanied by gallbladder stones and cholecystitis, etc. However, there is no specific clinical manifestation of the disease itself, and the symptoms of the disease are similar to those of cholecystitis, including jaundice, biliary colic, fever, etc. Most of the cases are combined with chronic cholecystitis. Most of them are combined with chronic cholecystitis. The diagnosis of adenomyosis relies on histopathologic biopsy, and imaging is an important preoperative evaluation tool. Adenomyosis of the gallbladder is a benign lesion but has some malignant potential. Elective surgery should be considered for the detection of this disease, and laparoscopic cholecystectomy is generally recommended. If you experience any of the above symptoms, or suspect adenomyosis of the gallbladder, it is recommended that you seek prompt medical attention.