Polycystic kidney patients with no abnormal kidney function can have children. Polycystic kidney patients with abnormalities in the kidneys, with age, the cysts in the kidneys will become more and more, and the diseased tissue replaces most of the normal renal tissue, leading to renal insufficiency, or even uremia. Female patients with polycystic kidney, who can have children when their kidney function is normal, may increase the burden on the kidneys during pregnancy, leading to further deterioration of kidney function. Therefore, women with polycystic kidney should closely monitor urinary protein and renal function during pregnancy and terminate the pregnancy at the right time. Polycystic kidney is a hereditary disease, in the clinic the most common is adult dominantly inherited polycystic kidney, the genetic risk is higher, but polycystic kidney patients can still have children. Polycystic kidney patients can have children during pregnancy or do IVF before pregnancy to do the relevant chromosomal genetic examination, to block the next generation of inheritance.