Loss of vision is related to a number of disease factors, and once it occurs, we should be alert to the emergence of acute angle-closure glaucoma, central retinal artery embolism, vitreous hemorrhage and other diseases, and patients should be given targeted treatment. Acute closed-angle glaucoma occurs in people over 50 years of age, and mainly female patients, due to the existence of family genetic predisposition to this disease, patients with this disease may appear elevated intraocular pressure, resulting in corneal edema, optic nerve atrophy, which may appear vision loss. Many elderly people have central retinal artery embolism, during the onset of arterial atherosclerosis, and atherosclerotic plaque on the inner wall of the artery, which can lead to embolism of the central retinal artery, retinal ischemia and necrosis, resulting in severe vision loss. Vitreous hemorrhage is often seen in hypertensive or diabetic people, rupture of blood vessels in the fundus of the eye, blood enters the vitreous humor, affecting the entry of light into the eye, the patient may experience blurred vision, and in severe cases, vision can be severely reduced. Patients with vision loss are advised to seek prompt medical attention to assess their condition and follow the doctor’s instructions.