Forty-three-year-old woman suddenly gained weight breasts are also large, no pain, no swelling may be caused by improper diet, may also be due to hypothyroidism, Cushing’s syndrome and other diseases. 1. Improper diet: If the forty-three-year-old woman usually do not pay attention to diet control, often eat high-calorie, high-fat food, resulting in excessive accumulation of body heat, it will be converted into fat in the body, then will cause obesity, with the increase in body weight, the breasts will gradually become bigger and bigger, no pain and no swelling. 2. Hypothyroidism: The occurrence of this disease is related to Hashimoto’s thyroiditis, thyroid destruction, iodine deficiency or excessive intake and other causes. With the progression of the disease, female patients will appear menstrual disorders, weight gain and other symptoms, which can be manifested as a forty-three-year-old woman suddenly gained weight breasts are also large, no pain and no bloating. 3. Cushing’s syndrome: the main cause of this disease is the hypothalamus – pituitary – adrenal axis mismatch, so that the adrenal cortex secretion of excessive glucocorticoids caused by a series of manifestations, prevalent in 20 to 45 years old women, so part of the forty-three year old woman will suddenly appear to be fat breasts are also large, no pain, no swelling of the situation. It is recommended that the forty-three year old woman suddenly grows fat breasts, no pain, no swelling of the crowd, go to the hospital, clear specific reasons.