Lumbar spondylosis may cause tingling of the skin from the anus to the scrotum. Lumbar spondylosis, including lumbar disc herniation, lumbar spinal stenosis, lumbar spondylolisthesis, etc., the early stage will usually appear lumbar pain, lumbar pain, with the gradual aggravation of the condition, lumbar spine compression of the sciatic nerve, the cauda equina nerve, may cause anal to scrotum skin tingling, and some people will be accompanied by sciatica, perineal numbness, and in severe cases, it may also cause defecation, urination, and abnormal sexual function disorders. Anus to scrotum skin tingling may also be due to prostatitis, urinary tract infections, urethral stones and other diseases caused by the cause of the disease is not clear before the blind use of medication, it is recommended to regular hospitals to do physical examination, imaging tests, laboratory tests, etc., according to the results of the examination to determine the specific cause of the disease, under the guidance of the doctor to do targeted treatment.