There is no strict regulation on how long to stop taking targeted drugs, which is related to the patient’s body tolerance level, disease type and disease treatment, etc. Some patients can stop taking the drugs after a few years, while some patients may need to take them for a long time. Targeted drug is one of the important methods to treat cancer. Its principle is to eliminate cancer cells by identifying the characteristic sites of genes on tumor cells and combining with them so as to block the growth and reproduction of cancer cells in a targeted way. 1. If the patient’s condition is found in time and at an early stage, usually a few years of taking the drug can have a good therapeutic effect and the drug can be stopped. If the condition is more serious, long-term medication may be needed. 2. If patients taking targeted drugs have serious adverse reactions or develop drug resistance, they should consider stopping the drug or adjusting the drug. Overall, the use of targeted drugs should strictly follow the doctor’s instructions, do not stop or adjust the type and dose of drugs, so as not to adversely affect the treatment of the disease.