Nifedipine extended-release tablets and metoprolol tartrate can be taken together, but need to pay attention to monitoring blood pressure and heart rate, need to follow the doctor’s instructions for joint use. Nifedipine extended-release tablets can diastole coronary arteries, relieve coronary artery spasm, diastole peripheral resistance vessels, so that the systolic blood pressure, diastolic blood pressure reduction, belong to the dihydropyridine class calcium antagonist. It can be used alone or in combination with other antihypertensive drugs for the treatment of hypertension and also for the treatment of angina pectoris. Adverse reactions to nifedipine extended-release tablets include peripheral edema, headache, chest pain, sensory abnormalities, leg pain, vertigo, nosebleed, rhinitis, rash, leg cramps, urinary frequency, and impotence. It is contraindicated in people who are allergic to this product. Metoprolol tartrate belongs to β1-receptor blocking drug, which has the effect of slowing down the heart rate, lowering blood pressure, and inhibiting cardiac contractility. It is used in the treatment of angina pectoris, hypertension, hypertrophic cardiomyopathy, myocardial infarction, aortic dissection, arrhythmia, cardiac neurosis, hyperthyroidism and so on. Adverse effects of metoprolol tartrate include conduction block, heart rate slowing, worsening of heart failure, lower blood pressure, fatigue, dizziness, and depression. It is contraindicated in hypotension, significant bradycardia, cardiogenic shock, severe or acute heart failure, second or third degree atrioventricular block, severe peripheral vascular, and sick sinus node syndrome disorders. Nifedipine extended-release tablets can be used in combination with beta-blockers, the vast majority of the population has good tolerance and efficacy, but individually can aggravate hypotension, angina pectoris and heart failure. Therefore, the two can be taken together as prescribed by the doctor, but pay attention to blood pressure and heart rate during use.