Most of the commonly used drugs, especially western drugs, have stimulating effects on the gastrointestinal tract, and different drugs with different dosages have different adverse reactions on the gastrointestinal tract. The most common complication of gastric ulcer patients is gastrointestinal bleeding and perforation, can induce or aggravate gastrointestinal bleeding of the drug, is a gastric ulcer patients are contraindicated oral medication, the drug has: first, anti-platelet aggregation, thrombolytic drugs, because of the condition of the need for application of the drug do not through the oral route. Second, antipyretic and analgesic drugs, mainly inhibit the synthesis of prostaglandins, prostaglandins have inhibited gastric acid secretion, protect the gastric mucosa, the number of decline is likely to cause an increase in gastric acid secretion, gastric acid stimulation of the mucosa, is not conducive to the healing of gastric ulcer wounds. Third, glucocorticoid hormones, easy to induce and aggravate peptic ulcer, not conducive to the healing of the ulcer surface.