Urethral orifice inflammation is recommended to be cleaned locally, assisted by drinking more water and oral antimicrobial combination, which is the fastest way to reduce inflammation. If there is inflammation in the urethra, the mucous membrane of the urethra will be red and there may be pain when urinating. Clean the urethra with water and also clean the perineum to reduce the aggravation of inflammation, and it is also recommended that underwear should be changed every day. It is recommended that you should drink more than 2000ml of water every day to discharge more urine to play a flushing role, which can bring the inflammation under control faster. You should take oral broad-spectrum antimicrobials, most commonly levofloxacin, 0.2g each time, twice a day orally, through these treatments can soon control the inflammation.