The origin and physiological function of the female prostate The prostate gland is an accessory gland of the male reproductive system. Although women do not have a prostate gland, they also have tissues similar to the prostate gland. There are some glandular tissues around the outlet of the female bladder, whose structure is similar to that of the male prostate. These glandular tissues originate from the same embryonic tissues as the male prostate during the embryonic period, and the composition of their secretions is the same as that of the male prostate fluid. The female prostate-like tissue is associated with the female erogenous zone (G-zone), which was named after Grafeaburg, a German physician who discovered it in 1944. The G-zone is located in the middle of the anterior wall of the vagina, and consists of the ducts of the female prostate and their surrounding tissues, and in 1950 he again suggested that there is an erectile tissue in this zone similar to the cavernous corpus cavernosum of the penis, which swells when sexually stimulated and apparently bulges out into the vagina, reaching the vagina, where it can be seen. Obviously to the vagina, to reach orgasm can appear urethral ejaculation, similar to male ejaculation, and later confirmed that the ejaculated fluid from the female prostate, which contains fructose and PSA, different from urine, also known as vaginal ejaculation, folk also known as “blow job”. (Anatomical location of the G-spot) The female prostate compared to the male prostate 1, the female prostate and the male prostate is originally homologous, due to the different levels of hormones in the body of men and women and developed into different forms, the female prostate due to the lack of sufficient androgen stimulation and failed to fully develop, therefore, the female prostate than the male prostate is much smaller and thinner. 2, the male reproductive tract and the urethra are the same channel, the male prostate fluid becomes part of the semen, which has an effect on fertility; while the female prostate has no significant effect on fertility. 3, the female prostate is generally not affected by endocrine disorders like the male prostate. Men may cause prostate hyperplasia in middle age and old age, but women generally do not, but individual cases may also occur female prostate hyperplasia, which may cause urination difficulties. The most common female prostate diseases are female prostatitis and female prostatic hyperplasia, so let’s learn more about them. The symptoms of female prostatitis are varied, manifesting as frequent urination, difficulty in urination, pressure behind the pubic bone, difficulty in sexual intercourse or pain in sexual intercourse, and also hematuria as well as pain in the lower back, lower abdomen, groin, and thighs; the symptoms are similar to those of lower urinary tract infections, but the mid-range urinalysis is not abnormal, and bacterial cultures are often negative. 1, diagnosis If a female patient has urinary frequency, urgency, pain in urination, perineum, suprapubic area or lower back distension and other lower urinary tract symptoms with pain in sexual intercourse, the receiving doctor should consider the diagnosis of female prostatitis, in the line of vaginal auscultation should pay special attention to the inspection of the paraproctal glands, the available fingertips to the anterior wall of the vagina, the distal 2/3 of the urethra will be pressed to the flat pubic symphysis, if the patient complains of obvious pain and screaming and wriggle the hip If the patient complains of obvious pain and screams, and twist the hips to avoid, and press the side wall of the vagina, the back wall or other parts of the vagina does not have such a reaction, the normal female in the pressure on the anterior wall of the vagina, some like the male prostate massage, only to urinate the feeling, and not pain. The ideal drug for treating prostatitis should have a small molecular weight, be fat-soluble, and have a low binding affinity to proteins so that it is easy to penetrate into the prostate gland. Fluoroquinolones meet these conditions and are composed of the basic structure of 4-pyridinecarboxylic acid, which is acidic, and thus can carry out “ion trapping” in the alkaline secretions of chronic prostatitis in order to Kill microorganisms, antibacterial spectrum, including chlamydia and mycoplasma, of which of the ofloxacin has been approved by the U.S. Food and Drug Administration (FDA) for bacterial prostatitis, their role is to inhibit bacterial DNA replication, transcription and repair of the necessary helicase, resistance to drug resistance, but should not be used in children, so as not to cause chondrogenic disorders, the drug can be passed through the placenta and into the breast milk, so pregnant women and lactating women are prohibited. The drug can pass through the placenta and enter breast milk, so pregnant women and lactating women are prohibited. Prostatic hyperplasia in women Clinically, the tissue around the female bladder that resembles the male prostate is called prostate-like tissue, and because it is similar to male prostatic hyperplasia in terms of symptoms, it is also known as “prostatic hyperplasia” in women. Its symptoms and causes are similar to those of male prostatic hyperplasia, and clinically it is mostly seen in middle-aged and old-aged people, especially elderly women, and its incidence tends to increase with the age of the population. 1, etiology Long-term chronic inflammatory stimulation of the urethra, so that the mucosa and submucosa of the bladder neck edema, fibrous tissue proliferation, smooth muscle hyperplasia and hypertrophy of the bladder neck. With age, the level of estrogen in women’s bodies decreases, and the imbalance of sex hormone levels can lead to periurethral glandular hyperplasia. 2.Diagnosis Because female prostatic hyperplasia is not common in the clinic, it is very easy to misdiagnose it only based on the patient’s complaints, clinical manifestations, physical examination and urine examination, and it needs to be combined with ultrasound, cystourethroscopy, urodynamics and other tests for comprehensive analysis to make a correct diagnosis. Ultrasound diagnostic criteria: the bladder neck hypoechoic mass is enlarged, longitudinal section shows that the tip of the bladder neck downward triangular hypoechoic mass thickened lip-like to the bladder, transverse section shows that the bladder neck hypoechoic mass is full shaped like a male prostate gland, the transverse diameter ≥ 1.5 cm, anterior and posterior diameters ≥ 1.0 cm, the circumference ≥ 3.5 cm. cystourethroscopy shows that there are varying degrees of trabecular hyperplasia in the bladder wall, and the posterior lip of the bladder neck bulging in the form of a dyke, and there is chronic inflammation in the proximal part of the urethra, and there are also chronic inflammation in the proximal part of the urethra. And there are chronic inflammatory changes in the proximal urethra, which can help the diagnosis of this disease, and also exclude the lesions of the urethra and bladder. 3, treatment For early patients with mild symptoms, urethral dilatation is feasible, and at the same time take α1-blockers, estrogen, etc. α1-blockers can make the smooth muscle of the bladder neck relax, reduce the resistance of the bladder and urethra; estrogen can improve the nutrition of the epithelium, promote blood circulation, and enhance urethral tone, so the efficacy of the treatment is remarkable. For those who have obvious difficulty in urination, Qmax<15ml/s, residual urine volume>60ml, and cystourethroscopy confirms that there is bladder neck outlet obstruction, they should be treated with bladder neck electrodesiccation. For those with urinary tract infection, renal or ureteral fluid, and renal insufficiency, preoperative application of antimicrobial drugs and indwelling catheter for continuous drainage should be performed, and surgical treatment should be carried out after the infection is controlled and renal function is improved. In the future, when someone mentioned to you the prostate or prostate-related diseases, do not think of only men Oh, women also have prostate-like tissue, will also get prostate-related diseases, today eye-opening right? The secret of the female prostate can not be shared alone, share it with more friends to reduce the misdiagnosis and treatment of such diseases.