Esophageal glycogen echinococcosis, also known as esophageal leukoplakia, is a white plaque appearing on the mucous membrane of the esophagus due to hyperkeratinization of the esophageal epithelium, and it is prevalent in males over 40 years of age. There are usually no obvious self-conscious symptoms, and in the later stages, the white spots are particularly sensitive to hot and irritating foods. If the white spots expand rapidly, thicken, crack, break, and harden, retrosternal pain may occur, and further examination should be performed to exclude cancer. The causes of esophageal glycogen acanthosis are as follows: 1. Long-term persistent stimulation: overheating or overcooling diet, spicy stimulating food, strong tobacco and alcohol, as well as unhygienic oral cavity, etc., may cause excessive keratinization of esophageal epithelial mucosa and esophageal glycogenous echinoderma. 2. Disease causes: endocrine disorders, anemia, systemic progressive sclerosis, cirrhosis, fungal infections, etc. may cause this disease. Esophageal glycogen echinococcosis usually has no obvious self-conscious symptoms, the disease late white spots will be particularly sensitive to hot, irritating food, patients may feel pain behind the sternum when eating. The disease is mainly diagnosed by esophagoscopy or gastroscopy. Esophageal glycogenous acanthosis usually does not need special treatment, but should remove the cause of the disease, change the bad eating habits, quit smoking and alcohol, do not eat too hot and spicy food.