Chronic superficial gastritis with erosion usually does not evolve into early gastric cancer. Chronic superficial gastritis with erosion is a limited superficial defect of gastric mucosal epithelium on the basis of chronic superficial gastritis. Gastrointestinal symptoms such as fullness and bloating after meals, irregular abdominal pain and dyspepsia are usually common, mostly caused by irregular diet and alcohol consumption. Generally, chronic superficial gastritis with erosion will not evolve into gastric cancer. However, if the symptoms persist for a long time and worsen due to untimely treatment, there is a risk of developing into atrophic gastritis or even early gastric cancer. Chronic superficial gastritis with erosion is usually treated with medication, and proton pump inhibitors such as omeprazole can be taken under the guidance of doctors to reduce the secretion of gastric acid and its corrosive effect on the stomach, and if there are Helicobacter pylori infections, quadruple drugs should be standardized, i.e., 2 antibiotics such as amoxicillin and clarithromycin + bismuth + proton pump inhibitors such as omeprazole. At the same time, patients should correct their dietary habits and develop good living habits to avoid aggravating symptoms or even causing bleeding. If chronic superficial gastritis with erosion is confirmed, one should go to the hospital in time and improve the examination and take treatment under the doctor’s guidance.