The primary causes of hepatic encephalopathy include severe viral hepatitis, severe toxic hepatitis, drug-related liver disease, acute fatty liver during pregnancy, all types of cirrhosis, post-portal-body vein shunt, primary liver cancer and other end-stage of diffuse liver disease, while hepatic encephalopathy occurs most frequently in patients with cirrhosis, accounting for about 70% of cases. There are many factors that induce hepatic encephalopathy, such as upper gastrointestinal bleeding, high protein diet, massive potassium diuresis, ascites discharge, use of sleeping, sedative and narcotic drugs, constipation, uremia, infection or surgical trauma. So, what is the basis for the diagnosis of proximal coma? The following are the diagnostic bases of proximal coma: 1. Meet the diagnostic criteria for mental disorders due to somatic diseases. 2, there is sufficient evidence of serious liver disease, the occurrence and course of psychiatric symptoms are closely related to liver disease. 3, mental disorders of acute hepatic encephalopathy: ① inhibited state, at the beginning of the disease, mostly manifested as sluggishness, little movement, reticence, etc.; ② excited state (such as agitation, talkative, shouting or light manic state); ③ drowsiness, lethargy, delirium or confusion to coma and other varying degrees of disorders of consciousness; ④ fragmentary hallucinations or delusions; ⑤ after the mental disorders or coma aura, there are slurred pronunciation, fluttering tremor, nystagmus, and There may be spasmodic seizures, myoclonus, increased muscle tone, pathological reflexes, etc. (4) Mental disorders in sexual hepatic encephalopathy: (1) disorders of consciousness is one of the main symptoms; (2) mental retardation or dementia; (3) personality changes, emotional instability, irritability, impetuous movements, lack of manners, etc.; (4) fluttering tremor, tardive dyskinesia, myoclonus, dysarthria, pyramidal fasciculus, cerebellar symptoms, etc. may appear at the same time. 5. Period EEG mostly shows diffuse bilateral synchronous high amplitude theta; waves and synchronous high amplitude delta; waves. In coma, characteristic triphasic waves may appear, mostly in the frontal lobe, symmetrical to the left and right. 6, In addition to other causes of encephalopathy.