The discomfort and foreign body sensation in the right side of the colon may be caused by constipation, inflammation and infection, polyps, tumors and so on. 1. Constipation: If there is accumulation of feces in the right side of the colon, which cannot be discharged in time, you may feel a foreign body sensation locally, and sometimes you may feel slight pain when pressing. 2. Inflammatory infections: mainly due to local inflammatory stimulation, resulting in the right side of the colon congestion and swelling or ulceration, thus causing discomfort. 3. Colon polyps: If the polyps are small, there is no obvious discomfort, but with the gradual increase of the polyps, it may lead to a foreign body sensation in the colon. 4. Colon tumor: including benign tumors and malignant tumors, with the gradual increase of the tumor, you will feel the local discomfort and foreign body sensation. Different causes, treatment methods are different, it is recommended to go to the hospital in time to identify the causes, targeted treatment.