Omeprazole and Itopride both belong to the drugs for treating gastric discomfort and can be taken together when the patient has gastritis, gastric ulcer and other diseases. Omeprazole belongs to proton pump inhibitors, which protects the gastric mucosa by inhibiting the secretion of gastric acid and reduces the discomfort of acid reflux and heartburn in the stomach. Itopride is a gastric stimulant, which promotes gastrointestinal motility, accelerates digestion and absorption of gastrointestinal contents, and relieves bloating, indigestion and other discomforts. Both are used to treat indigestion, gastritis, gastric ulcer and other diseases, and rarely have drug reactions. Omeprazole and Itopride can be taken at the same time, but the patient must consult the physician before using the drug, under the guidance of the physician to follow the doctor’s instructions to use the drug, you can not choose their own drugs for treatment.