OVERVIEW
OVERVIEW
Reactive plasmacytosis refers to a group of clinical syndromes characterized by an increase in the number of mature plasma cells in the bone marrow, caused by a variety of reasons or primary diseases. Under normal conditions, plasma cells do not appear in the peripheral blood, but they can appear in pathological conditions. Intramedullary plasmacytosis can occur in the presence of different antigenic stimuli, metabolic reactions, autoimmune disorders, and neoplasms.
Whether medical insurance
Yes
Department
Hematology
Synonyms
Plasmacytosis, Reactive plasmacytosis
Clinical symptoms
Associated with the primary disease, such as fever, malaise, lethargy and pallor.
Hazards
Related to the hazards of the primary disease, which may cause hemolytic anemia, acquired vascular hemophilia, or hypoglycemia.
Complications
Hemolytic anemia, acquired vascular hemophilia, hypoglycemia, etc.
Examination
Physical examination, blood routine, serum immunoglobulin determination, bone marrow cytology, immunofixation electrophoresis, etc.
Diagnosis
Diagnosis can be made on the basis of history and clinical manifestations, combined with >3% increase in mature plasma cells in the bone marrow, and exclusion of other diseases.
Treatment principle
Actively treat the primary disease and use immunosuppressant therapy if necessary.
Curability
Aggressive treatment of the primary disease may relieve symptoms.
Dietary recommendations
Dietary programs are formulated according to the primary disease.
Etiology
Etiology
Can be caused by infection, tumor, allergic disease, hematopoietic system disease, etc.
Symptoms and Diagnosis
Typical symptoms
Related to the original disease, there may be fever, fatigue, emaciation, pallor, jaundice, bruises, petechiae and other manifestations.
Diagnostic basis
1. Existence of etiology or primary disease causing reactive plasma cell increase, such as viral infection, allergic disease, connective tissue disease, tuberculosis, chronic liver disease, malignant tumor, aplastic anemia, myelodysplastic syndrome, etc. 2. Clinical manifestations related to the primary disease. 3. Immunoglobulin is normal or increased, and immune-fixed electrophoresis shows polyclonality; plasma cell increase in bone marrow is >3% for mature plasma cells.
Treatment
Treatment guidelines
Treat the primary disease and remove the cause; use immunosuppressant therapy if necessary.
Drug therapy
When hemolytic anemia, acquired vascular hemophilia, and hypoglycemia are caused, adrenocorticotropic hormone or other immunosuppressive therapy may be tried.
Prognosis
Whether reactive plasmacytosis improves or not depends on the treatment effect of the primary disease, and plasmacytosis may disappear only after the primary disease is cured.
Nursing care
Daily care
1. The environment should be maintained at a suitable temperature and humidity, and ventilated frequently. Patients should wear breathable, cotton clothes, and should be kept warm if they have chills.2. Rest and activitiesPatients should have sufficient rest, live a regular life, avoid exertion, and take activities to the extent that they do not feel fatigue, and maintain sufficient sleep to prevent aggravation of the condition.3. Prevention of infectionKeep the environment clean and hygienic and the patients’ organisms clean, to prevent the spread of bacteria in the body, and to do a good job of oral care, perineal-anal care and prevention of all kinds of infections.4. Psychology Nursing family members take the initiative to communicate with patients, promote the interactive relationship between patients and their families, and take the initiative to participate in the care of patients in order to reduce the patient’s inner sense of depression.
Diet regulation
According to the primary disease to develop a corresponding diet program.