Colla Corii Asini powder in the correct use and within the scope of the indications to take generally no significant harm, but Colla Corii Asini is more nourishing, the spleen and stomach weak people taking may cause discomfort, such as colds and other symptoms of real evil may aggravate the condition. Colla Corii Asini is a traditional Chinese medicine, for horses and donkeys and other animals, the skin is processed and boiled into the glue, with blood, nourishing yin, moistening the lungs, the effect of bleeding. It is used for facial atrophy (yellowish color without luster), palpitation (rapid heartbeat, often accompanied by panic), weakness, heartburn, labor cough, metrorrhagia (excessive menstrual flow or dribbling), and fetal leakage in pregnancy (small amount of vaginal bleeding in the early stages of pregnancy). Adverse effects and contraindications of Colla Corii Asini are still unclear. Caution should be taken when taking the medicine, such as weak spleen and stomach, exogenous solid evil, and pregnant women. If there is any discomfort, please go to the hospital as soon as possible, and under the guidance of Chinese medicine practitioners, individualized diagnosis and treatment plan should be formulated, so as to avoid delaying the condition.