The causes of intra-anal pain include anal fissure, hemorrhoids, perianal abscess, anal fistula, tumor, etc. MRI has a higher diagnostic value for anal fistula and tumor, so the doctor will choose to do MRI according to the actual condition of the patient when intra-anal pain occurs. When intra-anal pain occurs, symptom characteristics combined with rectal fingerprinting can diagnose anal fissure, hemorrhoids, perianal abscess and other diseases. Part of the cause of the exclusion or qualitative and localization of diagnosis need to carry out imaging tests, and MRI of soft tissue lesions of high diagnostic value, clinically used to assist in the diagnosis of anal fistula, perianal tumors and other diseases. Nuclear magnetic resonance can show the location of anal fistula, fistula walk, polyps, adenomas and other benign perianal tumors location, size, texture, etc., the choice of surgical program has important significance. MRI can also show the infiltration depth and lymph node invasion of rectal cancer, anal canal cancer and other malignant tumors, which is of high value for diagnosis, staging and choice of treatment plan. In case of intra-anal pain, one should consult the doctor in time, follow the doctor’s instruction to give examination to clarify the diagnosis, and choose the appropriate treatment plan after the doctor’s examination and evaluation, so as to avoid delaying the condition.