Submucosal elevation of the esophagus may be caused by the following reasons: lesions in the esophagus itself, lesions outside the esophagus. 1. Lesions in the esophagus itself: If smooth muscle tumor or mesenchymal tumor occurs in the esophagus, or if lipoma, neuroendocrine tumor or esophageal cyst occurs, the submucosal layer of the esophagus will bulge. 2. Lesions outside the esophagus: If tumors occur in the mediastinum, such as thymoma, or lymph node enlargement occurs in the mediastinum, the esophagus will be compressed, which will be manifested as submucosal elevation of the esophagus. After the occurrence of submucosal elevation, it is necessary to further improve the relevant examinations, including ultrasonography, chest CT, etc., combined with physical examination and clinical symptoms, usually can clarify the cause.