Proaldosteronism is short for primary aldosteronism. Primary aldosteronism is caused by adrenal hyperplasia or adenoma, which leads to increased secretion of aldosterone by the adrenal glands. Aldosterone has a sodium-retaining and potassium-removing effect, so the most typical symptoms of primary aldosteronism are hypertension and hypokalemia. The diagnosis of primary aldosteronism requires the following: 1. clinical symptoms, hypertension and hypokalemia in patients with hypertension, especially moderate or severe hypertension that is difficult to control with conventional antihypertensive drugs. 2. elevated aldosterone levels in the blood and the presence of renin suppression, that is, the presence of hyperaldosteronism and hyporeninemia. Primary aldosteronism is highly suspected when the plasma aldosterone-to-renin activity ratio is greater than 50. 3. CT of the adrenal glands shows adrenal hyperplasia or adenoma.