Pimples are medically referred to as acne, and after squeezing a pimple the skin breaks down and direct exposure to air can easily lead to skin infections. Therefore, you need to prevent infection after squeezing a pimple. Patients can take general treatment and medication under the guidance of doctors. 1. General treatment: patients should avoid eating irritating food in their diet. Irritating food may stimulate the localization leading to redness and make the inflammation more obvious. 2. Medication: patients can apply topical creams such as fusidic acid cream, mupirocin ointment, retinoic acid cream, etc., which can prevent the wound from being infected by inflammation and bacteria, and help to promote wound healing. If there is more bleeding, patients can take oral medications such as minocycline hydrochloride, doxycycline hydrochloride, isotretinoin, etc., so as to play an antibacterial and anti-inflammatory role. All of the above drugs should be used under the guidance of a doctor, and patients should not use them on their own to avoid delays in their condition. Acne patients should avoid squeezing the pimples in order to avoid localized infections. If skin infection occurs, it is recommended to go to the hospital in time, and choose the appropriate treatment method under the guidance of the doctor.