Coma induced by CNS depressants is one of the types of pituitary crisis and pituitary stroke crisis, which is induced by hypopituitary hypoplasia, lack of adrenocorticotropic hormone and thyroid hormone, and decreased stress capacity of the body, in case of infection, vomiting, diarrhea, dehydration, cold, starvation, and application of sleeping pills or anesthetics. Acute neuroendocrine lesions caused by sudden intratumoral hemorrhage, infarction and necrosis of pituitary tumors, resulting in tumor expansion, are called pituitary strokes. So, how to prevent CNS-induced coma? The following are the prevention methods of CNS-induced coma: 1. Strengthen physical exercise to enhance the ability to resist infection. 2.Rationalize the diet to ensure comprehensive nutrition and prevent overnutrition, which may lead to obesity. Avoid smoking and alcohol. 3.Avoid long-term exposure to chemical toxins. For patients who have been taking isoniazid, phenytoin sodium, chloroquine, sulfonamide and other drugs for a long time, once the signs of the disease are detected, the drugs should be stopped immediately. 4, daily care and health care process of the extremities need to keep warm, but also to prevent burns. In addition to tetraplegia during the acute infection period, it can also be accompanied by respiratory muscle paralysis, which should be immediately sent to hospital for rescue.