Exactly how long you take rabeprazole for duodenal bulbitis depends on the severity of the condition; mild lesions are usually taken for about 2 weeks, while severe lesions may need to take the drug for about 3 to 4 weeks. Duodenal bulbitis is mostly caused by Helicobacter pylori infection, often need to take quadruple therapy treatment, including proton pump inhibitors, bismuth and two antibiotic drugs, such as rabeprazole, colloidal bismuth pectin, amoxicillin, metronidazole, etc., the course of treatment is usually 14 days, Helicobacter pylori bacteria can be eradicated, and the condition is cured. However, some patients with more serious conditions, after the eradication of H. pylori gastric mucosa still exists some damage, may need to continue to take rabeprazole and other proton pump inhibitors. The above drugs must be taken under the guidance of a doctor, and are contraindicated if you are allergic to the components of the drug.