There are several kinds of estrogen drugs as follows: First, natural estrogens, which are basically natural estrogen preparations secreted in vivo, including estradiol, estrone, estriol, etc. They are closely related to the metabolic process in vivo and the development and maintenance of secondary sex characteristics; second, semi-synthetic estrogens, which are synthesized with estrogenic activity by removing certain groups or adding certain groups to the basic structure of steroid hormones through artificial methods; third, synthetic estrogens, which are also called non-steroidal estrogens. Synthetic estrogenic drugs with estrogenic activity, such as ethinyl estradiol and nil estrol, etc.; third, synthetic estrogenic drugs, also known as non-steroidal estrogens, whose basic structure is not the framework structure of steroids, have estrogenic activity, such as hexestrol, etc. Estrogenic drugs are diverse and generally require symptomatic management under the medical advice of an outpatient physician on a case-by-case basis.