The cost of CA125 and HE4 examination is not clearly defined, it needs to be judged according to the specific hospital, the price may be between 100~200 yuan. Different levels of hospitals, CA125 and HE4 examination costs have obvious differences, the higher the level of the hospital, the greater the cost may be. CA125 examination costs, may be between 70 ~ 100 yuan. HE4 examination costs, may be between 50 ~ 100 yuan. So the cost of these two tests may be between $100 and $200. CA125 refers to cancer antigen 125 or glycan antigen 125, which is a protein and one of the tumor markers, and the HE4 test refers to human epitope protein 4, which is also a tumor marker. The results of these two tests may change abnormally when the patient develops certain malignant lesions. It is necessary for patients to undergo CA125 as well as HE14 tests under the guidance of their doctors according to their conditions.