The cause of low ApoA1 may be liver cancer or cirrhosis, or it may be a physiological cause, and the cause should be identified in time to take relevant treatment. Treatments include surgery, medication, radiotherapy and so on. 1. If the cause is physiological, for example, protein decomposition, protein drop and low ApoA1 will occur in the case of strenuous exercise. Physiological factors do not need to be handled, attention to improving living habits and regular monitoring are enough. 2. The most powerful treatment for liver cancer is surgical resection or liver transplantation. Surgical resection is to cut liver cancer wherever you see it and remove the tumor at a macro level, which is called radical resection. In addition, the whole liver can be removed and replaced with a new one, which is called liver transplantation. After surgery, radiotherapy, chemotherapy and immunotherapy are also needed, all of which are to assist the treatment of surgery and control the recurrence of liver cancer. 2. If cirrhosis is caused by liver, the most common cause is viral hepatitis, which will further lead to cirrhosis. For patients with cirrhosis caused by viral hepatitis, the first step is to actively control the virus replication. During the process of viral replication, if alanine aminotransferase is elevated, antiviral therapy, such as oral lamivudine and adefovir, should be actively considered to protect the liver. The presence of low apolipoprotein a1 should be promptly consulted to avoid delay.