Anal fissure can use lubricants laxatives (such as Keseru, Ma Ren Pills, glycerin suppositories, etc.) or liquid paraffin to soften the stool, it is recommended that patients suffering from anal fissure should seek medical treatment for reasonable and standardized diagnosis and treatment. Anal fissure is mainly caused by prolonged constipation and dry stools, which cause bleeding and pain in the anal canal during defecation. Once the anal canal is damaged, its healing is slow. Use lubricant laxatives (e.g. Kaiser Permanente, Ma Ren Pills, glycerin suppositories, etc.) or liquid paraffin to soften the stools and keep the stools unobstructed. The above medicines are effective for early anal fissure, and the fissure may be relieved or cured after a period of time. However, for severe anal fissure that does not relieve for a longer period of time, it can only be treated symptomatically to relieve the pain during defecation, and some surgical treatment may be needed for a complete cure. Drugs should be applied under the guidance of a doctor.