I. The importance of dermatopathological diagnosis There are many kinds of dermatological diseases, about 2000 kinds of dermatological diseases in total, which is the largest number of diseases among all medical subspecialties. In order to get a good treatment effect for any disease, the first choice is to have a clear diagnosis, and skin diseases are no exception. Many people think that dermatological diseases are difficult to treat, but the fact that they are not diagnosed is one of the reasons why they cannot be treated in a targeted manner. Since skin diseases occur on the surface of the body, the observation of skin damage is the main means of diagnosing skin diseases. In the past, this observation was mainly done by the naked eye and by observing the skin surface rash with certain auxiliary methods (e.g., magnifying glass, etc.), which is a unique diagnostic method for dermatology and occupies an important position. However, with the advancement of pathology, skin pathology examination by further observation of subsurface skin tissue changes with a microscope is also commonly used in dermatology clinics and has become one of the most valuable methods for dermatological diagnosis. In modern dermatology, there is a saying that a dermatologist who does not understand skin pathology can only be considered half a dermatologist, which illustrates the importance of skin pathology for the correct diagnosis of skin diseases. Second, which skin diseases need to do dermatopathology? For most diseases, it is difficult to get an accurate and reliable diagnosis by simple visual observation. For example, lichen planus is the most common disease in dermatology with high incidence, but some atypical lichen planus is difficult to distinguish from neurodermatitis, chronic eczema, itchy rash, and amyloidosis of the skin with the naked eye, but the disease is characteristic in pathology and there is no diagnostic difficulty. Another example is that both aspergillosis and aspergillosis look like blisters and macules to the naked eye, but it is not completely certain which disease it is, and there is still a great difference in the treatment of these two diseases, and a clear diagnosis directly affects the control and prognosis of the disease. Theoretically, all diseases require a pathological diagnosis in order to reach an industry-recognized diagnosis, and only with histopathology does the diagnosis have accuracy and reliability. In general, skin pathology is essential in the following cases: 1. skin tumors and precancerous lesions, especially malignant tumors and tumors suspected to have a tendency to recur after treatment. 2. 2. leprosy and skin tuberculosis and other granulomatous diseases, for different types of leprosy and skin tuberculosis, in the diagnosis, classification, prognosis and efficacy observation are of considerable value. 3. Herpetic dermatoses and vasculitis histopathological examination can help to diagnose and classify. 4. Certain skin diseases with pathogens such as various deep fungal diseases, cutaneous black fever, porcine cysticercosis, etc. can be clearly diagnosed by finding the pathogens through histopathological examination. 5. Skin diseases with relatively specific tissue changes such as connective tissue disease, chronic atrophic acrodermatitis, cutaneous amyloidosis, radiation dermatitis, histopathological examination can assist in clinical diagnosis. 6. certain skin diseases with certain specific lesions such as psoriasis, lichen planus, etc. 7. Histopathological examination can be performed for certain diseases of unknown clinical diagnosis, which can sometimes provide diagnostic clues or provide the etiology of certain diseases. Since July 2007, our hospital has diagnosed more than 1500 cases of various skin diseases, and many difficult diseases have been diagnosed and patients have received effective treatments. parts appeared broken, it was suggested that he went to Sanming City Dermatology Hospital for examination. The patient had been treated at a dermatology hospital in Fuzhou for more than half a year and was diagnosed with sporotrichosis, and the treatment was sometimes good and sometimes bad. After arriving at our hospital, I saw the patient and, based on clinical symptoms, suspected that he was suffering from leprosy and gave a tissue smear and skin pathology examination, which proved that he was suffering from leprosy, and his symptoms improved significantly after six months of treatment. With the increase in the number of cases of skin pathology tissue examination, the practice level of pathologists has gradually improved and the correct rate of diagnosis has been enhanced. At present, dermatologists in all counties of our city are recommended to our hospital for examination and treatment when they encounter difficult dermatological diseases. Through expert consultation and skin histopathological examination, most of the diseases are effectively treated and the business guidance for dermatologists in primary hospitals is strengthened.