The most common causes of sudden short-term decrease in platelets are phagocytic syndrome, thrombotic thrombocytopenic purpura, acute severe aplastic anemia and leukemia. 1. Hemophagocytic syndrome: it can cause the platelets to decrease sharply in a short period of time. 2. thrombotic thrombocytopenic purpura: it can also cause a short-term sharp drop in platelets. 3. Acute severe aplastic anemia: it can also cause a short-term sharp drop in platelets. 4. Leukemia: due to abnormal bone marrow hematopoiesis, it can cause severe thrombocytopenia and anemia. The normal value of platelets is (100~300) x 10⁹/L. When the platelet value is 10 x 10⁹/L, the risk of bleeding in various parts of the body becomes very high, so you need to be hospitalized immediately to receive treatment. In conclusion, regardless of the cause of thrombocytopenia, when the platelet value is 10×10⁹/L, it is necessary to go to the hospital immediately to receive treatment, otherwise, it will be life-threatening, and the medication should be administered under the guidance of a physician.