Bactrim can be used to treat eczema that is caused by an infection or an infection secondary to eczema. The rash is characterized by a red, swollen, erythematous, papular rash, yellow vesicles, oozing and crusting, and a fever. If the white blood cells and neutrophils are high, it proves that the eczema is heavily infected. In addition to topical Bactrim, topical fusidic acid ointment or clindamycin phosphate gel can also be used for treatment. It is also necessary to take a certain amount of oral antibiotic treatment, such as cephalosporin antibiotics as well as azithromycin, clindamycin or roxithromycin. If the condition is more serious, you also need to order cephalosporin antibiotics or clindamycin etc.