Avanafil and Dapoxetine Hydrochloride can be taken at the same time. Avanafil is a type 5 phosphodiesterase selective inhibitor, mainly used for the treatment of erectile dysfunction in men, the use of Avanafil need to pay attention to, there are serious liver and kidney insufficiency is prohibited. Adverse reactions such as nasopharyngitis and muscle pain may occur when taking it. Dapoxetine is a 5-hydroxytryptamine uptake inhibitor, mainly used to treat the symptoms of premature ejaculation in men aged 18 to 64 years old, this drug is prohibited from combining with monoglobulin oxidase inhibitors, and may produce adverse reactions such as headache and nausea when taken. It is not clearly stated in the instruction manual that the combination of the two drugs will produce adverse reactions, and the mechanism of action of the two drugs is different, so it can be used at the same time. If use is required, it is recommended to consult a specialist before taking.