Pain is a distress signal sent by the organism to itself after damage, an unpleasant experience and the fifth vital sign in addition to body temperature, pulse, respiration and blood pressure. Neck, shoulder, back and leg pain is mostly caused by chronic injury to soft tissues, which produce sterile inflammation inflammation and release pain-causing substances; soft tissue spasm, contracture, joint displacement on the nerve, vascular irritation, stimulation and jamming can produce pain. This pain can be produced locally by the injury, by the nerves that belong to the site being affected, or by soft tissue injury elsewhere. Therefore, the place where one feels pain is not necessarily the lesion, and even the site of pain is not clearly indicated due to the cross distribution of nerves. For example, pain in the extremities should be considered not only locally but also in the trunk and spine; knee pain should be considered not only in the knee joint but also in the lumbar hip and the soft tissues of the legs. Yao Yajie, Department of Orthopedics, Suzhou Pingjiang Hospital, Suzhou, China Therefore, no matter what kind of treatment is needed, it is necessary to target the lesion in order to achieve satisfactory and long-term results. This is especially true for needle knife treatment, as its diameter is only 0.8-1.0mm, which requires “precise” strikes.