Acne with pus is often referred to as acne with pustules. Considering moderate to severe acne, general treatment, medication and physical therapy can be given to improve symptoms and remove acne. General treatment: patients should eat a light diet, avoid high sugar and high fat diet, avoid spicy and stimulating food; regular work and rest, avoid staying up late; pay attention to skin cleaning, avoid exposure to the sun, and so on. 2. Medication: Topical medication: Topical medication includes retinoic acid (such as adapalene gel), benzoyl peroxide, antibiotic ointment (such as fusidic acid cream, etc.), selenium disulfide, etc. The above medications should be used under the guidance of a doctor and in conjunction with the patient’s condition. Oral drug treatment: moderate to severe acne only external drug efficacy is poor, it is recommended that oral retinoids (such as isotretinoin, etc.), antibiotics (such as doxycycline, etc.), anti-androgen drugs (such as ethinyl estradiol, cyproterone, etc.), or glucocorticosteroids (such as prednisone, etc.), etc., oral need to be combined with the actual situation of the patient, and at the same time, regular review, to avoid the adverse effects of the drug. 3. Physical therapy: red and blue light irradiation, photodynamic therapy, laser therapy, etc. can be used to control sebum secretion and reduce the inflammatory reaction. It is recommended that patients with pustular acne go to the dermatology department of a regular hospital in time to get a clear diagnosis and standardized treatment under the guidance of a doctor.