Repeated acne, especially in women, is particularly prominent and obvious in this regard. The reasons for acne are the following. First, endocrine factors, due to work and life stress, often emotional ups and downs, day and night of the, great joy and sadness caused by endocrine disorders. Second, the sebaceous glands caused by the increase of androgens, hair follicle canal wall keratinization and blockage of pores, resulting in poor sebum discharge, thus causing inflammation of the hair follicle sebaceous glands, associated with Propionibacterium infection. Third, there are some diseases that induce and cause acne. Constipation, chronic diarrhea, excessive stomach acid, ulcers and other diseases, resulting in the body’s toxins can not be eliminated, gathered into disease, so be sure to pay attention to and treatment of these diseases. Fourth, the change of seasons, some people are very uncomfortable with the change of seasons, the temperature rises and falls suddenly, the sebaceous glands secretion of the ducts appear serious malfunction, will also cause the repeated formation of acne. The last thing to emphasize is that after the acne must not be ignored, to intensify the treatment, topical drugs oral drugs, topical drugs preferred Adapalene gel, dotted application of clinical effect is very good.