Lying down and sleeping with back pain can be considered to be too soft mattress, lumbar disc herniation and ankylosing spondylitis and other conditions, it is recommended that further examination to take the appropriate physical, drug and other treatments. 1. If the mattress is too soft, the lumbar region can not be fully supported when sleeping, and the lumbar muscles can not be fully relaxed, etc., it is recommended that local hot compresses, massage and acupuncture and other physical therapy, and if necessary, can be taken orally to relax the tendons and blood capsule and other drugs. 2. If the imaging shows that the lumbar disc is herniated, it is recommended to stay in bed strictly, and at the same time, it can take non-steroidal anti-inflammatory and pain-relieving drugs such as Celecoxib and other nutritive drugs such as methylcobalamin, and then perform surgery to remove the protruding nucleus pulposus if necessary. 3. In addition, it is not excluded that ankylosing spondylitis is caused by genetic and immune factors. It is suggested that non-steroidal drugs such as diclofenac and other non-steroidal pain relieving drugs, as well as anti-rheumatic drugs such as methotrexate be taken, and if necessary, surgery can be carried out for hip replacement and orthopedic spine, etc. Therefore, it is recommended to go to the doctor in time. Therefore, it is recommended to go to the hospital in a timely manner for further examination under the guidance of the doctor to clarify the diagnosis and treatment.