The normal value of alanine aminotransferase is 5~40U/L, 130U/L suggests mildly high, indicating hepatocellular injury. It is common in viral hepatitis, alcoholic liver disease, drug hepatitis, etc. The overall prognosis is good, and it can be cured by active treatment, and is generally not serious. 1. Viral hepatitis: refers to the infectious disease of liver caused by virus, characterized by acute hepatocyte necrosis, degeneration and inflammatory reaction. Clinical manifestations are fever, chills, jaundice, etc. After active treatment, the prognosis is good. 2. Alcoholic liver disease: it is a liver disease caused by heavy drinking. It is characterized by fatty degeneration of liver cells, with clinical manifestations of fatigue, loss of appetite, and enlargement of liver in different degrees. After quitting drinking, most of them can be recovered. 3. Drug hepatitis: refers to liver injury induced by chemical drugs. It includes hepatocellular damage and cholestasis. After stopping the drug and treatment, most of them can be recovered. If the rise of ghrelin may be caused by autoimmune liver disease and other factors, you should go to the hospital in time to clarify the cause of the disease and follow the doctor’s instructions for treatment.