Sclerosing penis, a fibrous sclerosing disease of the penis of unknown origin, is also known as fibrous cavernositis of the penis, chronic cavernositis, and fibrinitis. It is more common in middle-aged people around 30-50 years old. The specific etiology and pathogenesis of the disease are not fully understood, but it is clinically believed that it is mostly related to atherosclerosis, hypertension, trauma, genetic factors, etc. Alcoholism, diabetes, autoimmune disorders, etc. can also lead to the occurrence of the disease. The main manifestation of this disease is single or multiple striated nodules on the dorsal side of the penis, which are hard and on time. Patients usually have no special sensation. When the penis is erect, there may be pain and penile curvature, which can affect sexual life. In severe cases, there may be impotence, difficulty in urination and difficulty in urination. The examination of blood and urine usually has no special abnormal results. If calcification has occurred, X-rays may show calcified hard nodes. Early diagnosis and early treatment. Patients in better health and with a shorter course of disease generally have a better prognosis. It is important to note that the disease does not have the tendency of malignant lesions. It is important to pay attention to prevention and actively treat atherosclerosis, hypertension and diabetes; take appropriate supplements of various vitamins, especially vitamin E; drink less alcohol and correct the bad habit of alcoholism; and also avoid trauma to the penis.