What are the main factors affecting diastolic blood pressure in normal people

There are two main factors that affect diastolic blood pressure in normal people: one is peripheral vascular resistance; the other is heart rate. That is, the greater the peripheral vascular resistance, the faster the heart rate correspondingly the higher the diastolic blood pressure will be. For patients with high diastolic blood pressure, the preferred antihypertensive drug is an angiotensin-converting enzyme inhibitor or, alternatively, an angiotensin II receptor antagonist can be applied. In addition to this, a thiazide diuretic, such as hydrochlorothiazide tablets, can also be applied in combination. In addition, patients are also advised to combine with beta-blockers, like bisoprolol or metoprolol, all of which, above all, can significantly lower the diastolic blood pressure level of patients. When high diastolic blood pressure is detected, patients can be evaluated after 1-3 months of lifestyle interventions to assess whether they can keep their blood pressure within the desired range, and if not, antihypertensive medication should be initiated.