Chronic simple moss is a common chronic inflammatory cutaneous neurological dysfunction dermatosis characterized by paroxysmal severe itching and mossy skin. According to the type of lesions, location and season of onset of chronic lichen simplex, its topical drugs can be divided into glucocorticoid preparations, tar-like preparations, other drugs. 1. Glucocorticoid preparations: glucocorticoid ointment, cream sealing package or tretinoin cream, ice camphor eucalyptus fluoride easy paste, tincture of compound fluoride acetate easy tincture, hasselnide solution can be used in the case of lesions with hypertrophic mossy lesions. 2. Tar preparations: 5% to 10% black bean distillate, bran distillate, pine distillate, coal tar, etc., although the effect is slow, but the efficacy is obvious. Tar preparations and glucocorticoid topical preparations for joint application, the effect is better. 3. Other drugs: other antipruritic agents such as 1% dacronine cream and doxepin cream are also available. If you need to use drugs, you should go to the hospital for a clear diagnosis, and the doctor issued a prescription to follow the doctor’s instructions to use drugs, not blindly use drugs, so as not to cause adverse effects on the body.