Cough with afternoon cough aggravation may be caused by respiratory tract infections, cough variant asthma, tuberculosis, gastroesophageal reflux and other diseases. 1. Coughs caused by respiratory infections, such as bacterial-induced bronchitis, pharyngitis, pneumonia and other diseases, may be aggravated by coughing in the afternoon. 2. Cough caused by cough variant asthma, which can be manifested as paroxysmal dry cough, triggered by cold air, irritating odor, etc., and aggravated in the afternoon or at night. 3. Caused by tuberculosis and accompanied by low fever in the afternoon and night sweats (abnormal sweating after going to sleep and stopping after waking up) and other symptoms. 4. Gastroesophageal reflux-related cough, after eating a full meal at noon, the reflux material can irritate the airway and worsen the cough in the afternoon. In conclusion, if the cough worsens in the afternoon, it is recommended that the patient should consult a doctor in time for examination, such as pathogen testing, blood test, chest CT and other tests, to clarify the cause of the disease and treat the cause.