The common causes of thigh pain above the knee are as follows: a. Thigh muscle strain, such as quadriceps strain, patient over-exercise or excessive weight bearing, can cause serious strain of the quadriceps muscle in front of the thigh, there will be pain symptoms in front of the thigh, the patient’s knee joint activities will be weakened. Second, osteoarthritis of the hip joint or femoral head necrosis can cause symptoms of radiated pain in front of the thigh, accompanied by limited hip joint activities and hip pain, through X-ray examination, MRI examination, the disease and severity of the hip joint can be found, active early diagnosis and early treatment, can make the thigh pain symptoms above the knee joint can be completely relieved, the patient’s quality of life will also be improve, and attention should be paid to protect thigh muscles and joints to avoid lesions and injuries in ordinary life. 3. Bone tumor of distal femur, usually occurs in adolescents, if there is unexplained pain and no obvious cause, you should consult a doctor promptly and confirm or exclude the diagnosis by X-ray, CT or MRI.