Paroxetine’s efficacy is to improve symptoms caused by depression, obsessive-compulsive disorder, panic disorder, social phobia and other disorders. Paroxetine is a potent and highly selective 5-hydroxytryptamine reuptake inhibitor. The mechanism of action of paroxetine is to increase the concentration of 5-hydroxytryptamine in the synaptic gap and enhance the central 5-hydroxytryptaminergic nerve function. The efficacy of paroxetine is as follows: 1. Depression: Paroxetine can improve depression-induced fatigue, lack of interest, lack of pleasure, lack of appetite and so on. 2. Obsessive-compulsive disorder: Paroxetine can improve the impulsive, imaginative, repetitive behaviors caused by obsessive-compulsive disorder. 3. Panic disorder: Paroxetine can improve chest tightness, shortness of breath, palpitations, sweating, nausea, etc. caused by panic disorder. 4. Social phobia: Paroxetine can improve social phobia caused by persistent nervousness and anxiety in social situations, avoidance of socializing, etc. Adverse drug reactions commonly include elevated cholesterol levels, high blood pressure, tachycardia, blurred vision, loss of appetite, weight gain, drowsiness or insomnia or euphoria, dizziness, tremor, headache, moodiness, yawning, sometimes abnormal dreams (including nightmares), nausea and vomiting, constipation or diarrhea, dry mouth, sweating, itching, arthralgia, tinnitus, and so on. Use with caution in epileptic or manic patients, contraindicated in pregnant women; coadministration of other drugs should be guided by a medical professional; long-term use of drugs need to be monitored for adverse drug reactions. Note that there should be a clear diagnosis, under the guidance of the physician to use the drug.