The 308 laser is also known as the usual 308 excimer laser, which is a single 308 nm wavelength and is considered the best wavelength for ultraviolet violet treatment of vitiligo. Research shows that excimer laser can make the epidermal melanocyte volume increase, dendrites lengthen, tyrosinase activity increase, melanocyte synthesis of these melanin ability to strengthen, while the immunosuppressive effect on the epidermis is also one of the mechanisms of action for the treatment of vitiligo. The suitable crowd is some face, neck and trunk, limb parts, the onset of age less than 18 years old, including physical weakness of vitiligo patients, the efficacy is better, the use of 308 nanometer excimer treatment system for progressive vitiligo effect is better.