There is no most effective way to get rid of spots due to individual differences. Spots on the face may be caused by chloasma, freckles, seborrheic keratosis, etc. They can be relieved by medication and physical therapy. 1. Melasma: If the spot on the face is caused by melasma, attention should be paid to sun protection and sunscreen and parasol can be used when going out. Patients can follow the doctor’s instruction to use topical hydroquinone cream, azelaic acid cream and other medicines, which can play a role in lightening and removing the effect of melasma. During the period, patients can cooperate with laser treatment, such as intense pulse light, Q laser, etc., which can decompose pigment particles and achieve the effect of melasma fading. 2. Freckles: Freckles may also lead to spots on the face, usually with laser treatment, such as Nd:YAG laser, etc., through the appropriate energy of the laser, so that the pigment particles are broken, which can play a role in removing freckles. 3. Seborrheic Keratosis: Long spots on the face may also be caused by seborrheic keratosis, which can be treated by freezing, destroying the diseased tissues through instantaneous low temperature, which can play a role in removing the effect of seborrheic keratosis. As there are many reasons for long spots on the face, it is recommended that patients choose regular hospitals for consultation and examination, and choose the appropriate treatment under the guidance of doctors.